Anti-Cancer:
Biomimetic compositions
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Insect 1 (Venom 1)
Dio 357, ILS=105%
Peptides Enzymes Low-weight
Molecules
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Insect 2 (Venom 2)
Low-weight Peptides Enzymes
Molecules
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No.1
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No.2
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No.3
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Activity of Biomimetic compositions
Recurrent adenocarcinoma 755
| Treatment | ILS,% | Survival animals |
| Composition No.1 | 110 | 2 / 9 |
| Composition No.2 | 75 | 1 / 6 |
| Composition No.3 | 70 | 2 / 10 |
Leukaemia P388
| Treatment | ILS,% | Survival animals |
| Composition No.1 | 190 | 2 / 12 |
| Composition No.2 | 107 | 3 / 12 |
| Composition No.3 | 145 | 2 / 12 |
Main co-workers:
Dr. S. O. Bachurin, Dr. S. E. Tkachenko, Dr. S. G. Klochkov.
Neuroprotectors:
Dimebon - novel neuroprotector for Alzhemer's disease treatment.
Main co-workers:
Dr. S. O. Bachurin, Dr. S. E. Tkachenko.
Literature:
- Bachurin S. O., Bukatina E. E., Grigor'ev V. V., Grigorieva I. V., Ivanov N. V., Lukoyanov N. V., Tkachenko S. E., Zefirov N. S.,
Cognition enhancing properties of antihistaminic drug Dimebon. Neurobiology of Aging, 1998, 19, (4S), S180.
- Bachurin S. O., Afanas'ev A. Z., Grigor'ev V. V., Lermontova N. N., Lukoyanov N. V., Tkachenko S. E., Zefirov N. S.,
Directed selection of the novel neuroprotectors for Alzhemer's disease treatment. Journal of Neurochemistry, 1997, 69, (Suppl.), S48.
- Zefirov N. S., Afanas'ev A. Z., Afanas'eva S. V., Bachurin S. O., Tkachenko S. E., Grigor'ev V. V., Jurovskaja M. A.,
Agent for treating neurodegenerative disorders. WO. Patent 9715225 (1997) (C.A.126, 338861).
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